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Recombinant L-asparaginase 1 from Saccharomyces cerevisiae: an allosteric enzyme with antineoplastic activity
L-asparaginase (L-ASNase) (EC 3.5.1.1) is an important enzyme for the treatment of acute lymphoblastic leukaemia. Currently, the enzyme is obtained from bacteria, Escherichia coli and Erwinia chrysanthemi. The bacterial enzymes family is subdivided in type I and type II; nevertheless, only type II h...
Autores principales: | Costa, Iris Munhoz, Schultz, Leonardo, de Araujo Bianchi Pedra, Beatriz, Leite, Mariana Silva Moreira, Farsky, Sandra H. P., de Oliveira, Marcos Antonio, Pessoa, Adalberto, Monteiro, Gisele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099943/ https://www.ncbi.nlm.nih.gov/pubmed/27824095 http://dx.doi.org/10.1038/srep36239 |
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