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Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases

Neurodegeneration and neurodegenerative disorders have been a global health issue affecting the aging population worldwide. Recent advances in stem cell biology have changed the current face of neurodegenerative disease modeling, diagnosis, and transplantation therapeutics. Stem cells also serve the...

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Autores principales: Singh, Shripriya, Srivastava, Akriti, Srivastava, Pranay, Dhuriya, Yogesh K., Pandey, Ankita, Kumar, Dipak, Rajpurohit, Chetan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099954/
https://www.ncbi.nlm.nih.gov/pubmed/27878120
http://dx.doi.org/10.3389/fmolb.2016.00072
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author Singh, Shripriya
Srivastava, Akriti
Srivastava, Pranay
Dhuriya, Yogesh K.
Pandey, Ankita
Kumar, Dipak
Rajpurohit, Chetan S.
author_facet Singh, Shripriya
Srivastava, Akriti
Srivastava, Pranay
Dhuriya, Yogesh K.
Pandey, Ankita
Kumar, Dipak
Rajpurohit, Chetan S.
author_sort Singh, Shripriya
collection PubMed
description Neurodegeneration and neurodegenerative disorders have been a global health issue affecting the aging population worldwide. Recent advances in stem cell biology have changed the current face of neurodegenerative disease modeling, diagnosis, and transplantation therapeutics. Stem cells also serve the purpose of a simple in-vitro tool for screening therapeutic drugs and chemicals. We present the application of stem cells and induced pluripotent stem cells (iPSCs) in the field of neurodegeneration and address the issues of diagnosis, modeling, and therapeutic transplantation strategies for the most prevalent neurodegenerative disorders. We have discussed the progress made in the last decade and have largely focused on the various applications of stem cells in the neurodegenerative research arena.
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spelling pubmed-50999542016-11-22 Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases Singh, Shripriya Srivastava, Akriti Srivastava, Pranay Dhuriya, Yogesh K. Pandey, Ankita Kumar, Dipak Rajpurohit, Chetan S. Front Mol Biosci Molecular Biosciences Neurodegeneration and neurodegenerative disorders have been a global health issue affecting the aging population worldwide. Recent advances in stem cell biology have changed the current face of neurodegenerative disease modeling, diagnosis, and transplantation therapeutics. Stem cells also serve the purpose of a simple in-vitro tool for screening therapeutic drugs and chemicals. We present the application of stem cells and induced pluripotent stem cells (iPSCs) in the field of neurodegeneration and address the issues of diagnosis, modeling, and therapeutic transplantation strategies for the most prevalent neurodegenerative disorders. We have discussed the progress made in the last decade and have largely focused on the various applications of stem cells in the neurodegenerative research arena. Frontiers Media S.A. 2016-11-08 /pmc/articles/PMC5099954/ /pubmed/27878120 http://dx.doi.org/10.3389/fmolb.2016.00072 Text en Copyright © 2016 Singh, Srivastava, Srivastava, Dhuriya, Pandey, Kumar and Rajpurohit. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Singh, Shripriya
Srivastava, Akriti
Srivastava, Pranay
Dhuriya, Yogesh K.
Pandey, Ankita
Kumar, Dipak
Rajpurohit, Chetan S.
Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title_full Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title_fullStr Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title_full_unstemmed Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title_short Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases
title_sort advances in stem cell research- a ray of hope in better diagnosis and prognosis in neurodegenerative diseases
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099954/
https://www.ncbi.nlm.nih.gov/pubmed/27878120
http://dx.doi.org/10.3389/fmolb.2016.00072
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