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A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis(†)
BACKGROUND: Brain radiation necrosis (BRN) can be a complication of radiotherapy for primary and secondary brain tumors, as well as head and neck tumors. Since vascular endothelial growth factor (VEGF) is also a vascular permeability factor in the brain, bevacizumab, a humanized antibody that inhibi...
Autores principales: | Furuse, Motomasa, Nonoguchi, Naosuke, Kuroiwa, Toshihiko, Miyamoto, Susumu, Arakawa, Yoshiki, Shinoda, Jun, Miwa, Kazuhiro, Iuchi, Toshihiko, Tsuboi, Koji, Houkin, Kiyohiro, Terasaka, Shunsuke, Tabei, Yusuke, Nakamura, Hideo, Nagane, Motoo, Sugiyama, Kazuhiko, Terasaki, Mizuhiko, Abe, Tatsuya, Narita, Yoshitaka, Saito, Nobuhito, Mukasa, Akitake, Ogasawara, Kuniaki, Beppu, Takaaki, Kumabe, Toshihiro, Nariai, Tadashi, Tsuyuguchi, Naohiro, Nakatani, Eiji, Kurisu, Shoko, Nakagawa, Yoko, Miyatake, Shin-Ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099992/ https://www.ncbi.nlm.nih.gov/pubmed/27833757 http://dx.doi.org/10.1093/nop/npv064 |
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