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Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signalling pathway

Cucurbitacin E (CuE), a potent member of triterpenoid family isolated from plants, has been confirmed as an antitumour agent by inhibiting proliferation, migration and metastasis in diverse cancer. However, the effects and mechanisms of CuE on osteosarcoma (OS) have not been well understood. The pre...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Xu, Shumei, Wu, Yaochi, Zhang, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100002/
https://www.ncbi.nlm.nih.gov/pubmed/27653525
http://dx.doi.org/10.1042/BSR20160165