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Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs

Acidic mammalian chitinase (AMCase) is implicated in asthma, allergic inflammation, and food processing. Little is known about genetic and evolutional regulation of chitinolytic activity of AMCase. Here, we relate human AMCase polymorphisms to the mouse AMCase, and show that the highly active varian...

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Detalles Bibliográficos
Autores principales:	Okawa, Kazuaki, Ohno, Misa, Kashimura, Akinori, Kimura, Masahiro, Kobayashi, Yuki, Sakaguchi, Masayoshi, Sugahara, Yasusato, Kamaya, Minori, Kino, Yoshihiro, Bauer, Peter O., Oyama, Fumitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100053/ https://www.ncbi.nlm.nih.gov/pubmed/27702777 http://dx.doi.org/10.1093/molbev/msw198

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