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Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs

BACKGROUND: Rotavirus vaccines have poor efficacy in infants from low- and middle-income countries. Gut microbiota is thought to influence the immune response to oral vaccines. Thus, we developed a gnotobiotic (Gn) pig model of enteric dysbiosis to study the effects of human gut microbiota (HGM) on...

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Detalles Bibliográficos
Autores principales:	Twitchell, Erica L., Tin, Christine, Wen, Ke, Zhang, Husen, Becker-Dreps, Sylvia, Azcarate-Peril, M. Andrea, Vilchez, Samuel, Li, Guohua, Ramesh, Ashwin, Weiss, Mariah, Lei, Shaohua, Bui, Tammy, Yang, Xingdong, Schultz-Cherry, Stacey, Yuan, Lijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100090/ https://www.ncbi.nlm.nih.gov/pubmed/27826359 http://dx.doi.org/10.1186/s13099-016-0136-y

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