Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties

BACKGROUND: Little is known about the roles of Notch signaling in cholangiocarcinoma (CC). The expression of hairy and enhancer of split 1 (Hes-1) has not been investigated yet in resected specimens of CC. Notch signaling has been reported to be related to cancer stem cell (CSC) like properties in s...

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Detalles Bibliográficos
Autores principales: Aoki, Shuichi, Mizuma, Masamichi, Takahashi, Yayoi, Haji, Yoichi, Okada, Ryo, Abe, Tomoya, Karasawa, Hideaki, Tamai, Keiichi, Okada, Takaho, Morikawa, Takanori, Hayashi, Hiroki, Nakagawa, Kei, Motoi, Fuyuhiko, Naitoh, Takeshi, Katayose, Yu, Unno, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100105/
https://www.ncbi.nlm.nih.gov/pubmed/27821106
http://dx.doi.org/10.1186/s12885-016-2919-4

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