Three novel mutations of STK11 gene in Chinese patients with Peutz–Jeghers syndrome

BACKGROUND: Peutz–Jeghers syndrome (PJS) is a rare autosomal dominant inherited disorder characterized by gastrointestinal (GI) hamartomatous polyps, mucocutaneous hyperpigmentation, and an increased risk of cancer. Mutations in the serine–threonine kinase 11 gene (SKT11) are the major cause of PJS....

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Hu, Mei, Libin, Huang, Yanru, Yang, Pu, Li, Haoxian, Peng, Ying, Chen, Chen, Wei, Xianda, Pan, Qian, Liang, Desheng, Wu, Lingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100203/
https://www.ncbi.nlm.nih.gov/pubmed/27821076
http://dx.doi.org/10.1186/s12881-016-0339-6

Ejemplares similares

Ejemplares similares