Cargando…
Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513
BACKGROUND: Evaluate the anti-tumor activity of ozonide antimalarials using a chemoresistant neuroblastoma cell line, BE (2)-c. METHODS: The activity of 12 ozonides, artemisinin, and two semisynthetic artemisinins were tested for activity against two neuroblastoma cell-lines (BE (2)-c and IMR-32) an...
Autores principales: | Coulter, Don W., McGuire, Timothy R., Sharp, John G., McIntyre, Erin M., Dong, Yuxiang, Wang, Xiaofang, Gray, Shawn, Alexander, Gracey R., Chatuverdi, Nagendra K., Joshi, Shantaram S., Chen, Xiaoyu, Vennerstrom, Jonathan L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100253/ https://www.ncbi.nlm.nih.gov/pubmed/27821095 http://dx.doi.org/10.1186/s12885-016-2872-2 |
Ejemplares similares
-
Monoclonal Antibodies That Recognize the Alkylation
Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel)
por: Jourdan, Joëlle, et al.
Publicado: (2015) -
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials
por: Moehrle, Joerg J, et al.
Publicado: (2013) -
Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan
por: Chaturvedi, Nagendra K., et al.
Publicado: (2016) -
Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay
por: Walz, Annabelle, et al.
Publicado: (2019) -
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus
por: McGuire, Timothy R., et al.
Publicado: (2019)