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How and how much does RAD-seq bias genetic diversity estimates?
BACKGROUND: RAD-seq is a powerful tool, increasingly used in population genomics. However, earlier studies have raised red flags regarding possible biases associated with this technique. In particular, polymorphism on restriction sites results in preferential sampling of closely related haplotypes,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100275/ https://www.ncbi.nlm.nih.gov/pubmed/27825303 http://dx.doi.org/10.1186/s12862-016-0791-0 |