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Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse
Actin assembly and inward flow in the plane of the immunological synapse (IS) drives the centralization of T cell receptor microclusters (TCR MCs) and the integrin leukocyte functional antigen 1 (LFA-1). Using structured-illumination microscopy (SIM), we show that actin arcs populating the medial, l...
Autores principales: | Murugesan, Sricharan, Hong, Jinsung, Yi, Jason, Li, Dong, Beach, Jordan R., Shao, Lin, Meinhardt, John, Madison, Grey, Wu, Xufeng, Betzig, Eric, Hammer, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100289/ https://www.ncbi.nlm.nih.gov/pubmed/27799367 http://dx.doi.org/10.1083/jcb.201603080 |
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