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Five factors can reconstitute all three phases of microtubule polymerization dynamics

Cytoplasmic microtubules (MTs) undergo growth, shrinkage, and pausing. However, how MT polymerization cycles are produced and spatiotemporally regulated at a molecular level is unclear, as the entire cycle has not been recapitulated in vitro with defined components. In this study, we reconstituted d...

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Detalles Bibliográficos
Autores principales: Moriwaki, Takashi, Goshima, Gohta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100292/
https://www.ncbi.nlm.nih.gov/pubmed/27799364
http://dx.doi.org/10.1083/jcb.201604118