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Mechanistic insights into mammalian stress granule dynamics

The accumulation of stalled translation preinitiation complexes (PICs) mediates the condensation of stress granules (SGs). Interactions between prion-related domains and intrinsically disordered protein regions found in SG-nucleating proteins promote the condensation of ribonucleoproteins into SGs....

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Detalles Bibliográficos
Autores principales: Panas, Marc D., Ivanov, Pavel, Anderson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100297/
https://www.ncbi.nlm.nih.gov/pubmed/27821493
http://dx.doi.org/10.1083/jcb.201609081