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A microtubule dynamics reconstitutional convention
In vitro reconstitution is the fundamental test for identification of the core components of a biological process. In this issue, Moriwaki and Goshima (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604118) reconstitute all phases of microtubule dynamics through the inclusion of five key regulat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Rockefeller University Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100300/ https://www.ncbi.nlm.nih.gov/pubmed/27821492 http://dx.doi.org/10.1083/jcb.201610066 |
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author | Slep, Kevin C. |
author_facet | Slep, Kevin C. |
author_sort | Slep, Kevin C. |
collection | PubMed |
description | In vitro reconstitution is the fundamental test for identification of the core components of a biological process. In this issue, Moriwaki and Goshima (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604118) reconstitute all phases of microtubule dynamics through the inclusion of five key regulators and demonstrate that Polo kinase activity shifts the system from an interphase mode into an enhanced mitotic mode. |
format | Online Article Text |
id | pubmed-5100300 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51003002017-05-07 A microtubule dynamics reconstitutional convention Slep, Kevin C. J Cell Biol Commentary In vitro reconstitution is the fundamental test for identification of the core components of a biological process. In this issue, Moriwaki and Goshima (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604118) reconstitute all phases of microtubule dynamics through the inclusion of five key regulators and demonstrate that Polo kinase activity shifts the system from an interphase mode into an enhanced mitotic mode. The Rockefeller University Press 2016-11-07 /pmc/articles/PMC5100300/ /pubmed/27821492 http://dx.doi.org/10.1083/jcb.201610066 Text en © 2016 Slep This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Commentary Slep, Kevin C. A microtubule dynamics reconstitutional convention |
title | A microtubule dynamics reconstitutional convention |
title_full | A microtubule dynamics reconstitutional convention |
title_fullStr | A microtubule dynamics reconstitutional convention |
title_full_unstemmed | A microtubule dynamics reconstitutional convention |
title_short | A microtubule dynamics reconstitutional convention |
title_sort | microtubule dynamics reconstitutional convention |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100300/ https://www.ncbi.nlm.nih.gov/pubmed/27821492 http://dx.doi.org/10.1083/jcb.201610066 |
work_keys_str_mv | AT slepkevinc amicrotubuledynamicsreconstitutionalconvention AT slepkevinc microtubuledynamicsreconstitutionalconvention |