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Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain
BACKGROUND: Glutamate-induced excitotoxicity, oxidative damage, and neuroinflammation are believed to play an important role in the development of a number of CNS disorders. We recently reported that a high dose of glutamate could induce AMPK-mediated neurodegeneration in the postnatal day 7 (PND7)...
Autores principales: | Shah, Shahid Ali, Amin, Faiz Ul, Khan, Mehtab, Abid, Muhammad Noman, Rehman, Shafiq Ur, Kim, Tae Hyun, Kim, Min Woo, Kim, Myeong Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100309/ https://www.ncbi.nlm.nih.gov/pubmed/27821173 http://dx.doi.org/10.1186/s12974-016-0752-y |
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