Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

BACKGROUND: CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but the...

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Detalles Bibliográficos
Autores principales: Capone, Manuela, Maggi, Laura, Santarlasci, Veronica, Rossi, Maria Caterina, Mazzoni, Alessio, Montaini, Gianni, Cimaz, Rolando, Ramazzotti, Matteo, Piccinni, Marie Pierre, Barra, Giusi, De Palma, Raffaele, Liotta, Francesco, Maggi, Enrico, Romagnani, Sergio, Annunziato, Francesco, Cosmi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100333/
https://www.ncbi.nlm.nih.gov/pubmed/27826220
http://dx.doi.org/10.1186/s12948-016-0053-0

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