Interplay between RNA-binding protein HuR and microRNA-125b regulates p53 mRNA translation in response to genotoxic stress

Tumor suppressor protein p53 plays a crucial role in maintaining genomic integrity in response to DNA damage. Regulation of translation of p53 mRNA is a major mode of regulation of p53 expression under genotoxic stress. The AU/U-rich element-binding protein HuR has been shown to bind to p53 mRNA 3′U...

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Detalles Bibliográficos
Autores principales: Ahuja, Deepika, Goyal, Ashish, Ray, Partho Sarothi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100343/
https://www.ncbi.nlm.nih.gov/pubmed/27592685
http://dx.doi.org/10.1080/15476286.2016.1229734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100343/
https://www.ncbi.nlm.nih.gov/pubmed/27592685
http://dx.doi.org/10.1080/15476286.2016.1229734

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