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Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast

Eukaryotic gene expression requires that RNA Polymerase II (RNAP II) gain access to DNA in the context of chromatin. The C-terminal domain (CTD) of RNAP II recruits chromatin modifying enzymes to promoters, allowing for transcription initiation or repression. Specific CTD phosphorylation marks facil...

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Detalles Bibliográficos
Autores principales:	Inada, Maki, Nichols, Robert J., Parsa, Jahan-Yar, Homer, Christina M., Benn, Ruby A., Hoxie, Reyal S., Madhani, Hiten D., Shuman, Stewart, Schwer, Beate, Pleiss, Jeffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100562/ https://www.ncbi.nlm.nih.gov/pubmed/27402158 http://dx.doi.org/10.1093/nar/gkw603

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