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Contiguous and accurate de novo assembly of metazoan genomes with modest long read coverage

Genome assemblies that are accurate, complete and contiguous are essential for identifying important structural and functional elements of genomes and for identifying genetic variation. Nevertheless, most recent genome assemblies remain incomplete and fragmented. While long molecule sequencing promi...

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Detalles Bibliográficos
Autores principales: Chakraborty, Mahul, Baldwin-Brown, James G., Long, Anthony D., Emerson, J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100563/
https://www.ncbi.nlm.nih.gov/pubmed/27458204
http://dx.doi.org/10.1093/nar/gkw654