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A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues
Histone proteins are synthesized in large amounts during S-phase to package the newly replicated DNA, and are among the most stable proteins in the cell. The replication-dependent (RD)-histone mRNAs expressed during S-phase end in a conserved stem-loop rather than a polyA tail. In addition, there ar...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100578/ https://www.ncbi.nlm.nih.gov/pubmed/27402160 http://dx.doi.org/10.1093/nar/gkw620 |