Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia

A wide range of diseases course with an unbalance between the consumption of oxygen by tissues and its supply. This situation triggers a transcriptional response, mediated by the hypoxia inducible factors (HIFs), that aims to restore oxygen homeostasis. Little is known about the inter-individual var...

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Detalles Bibliográficos
Autores principales: Roche, Olga, Deguiz, María Laura, Tiana, María, Galiana-Ribote, Clara, Martinez-Alcazar, Daniel, Rey-Serra, Carlos, Ranz-Ribeiro, Beatriz, Casitas, Raquel, Galera, Raúl, Fernández-Navarro, Isabel, Sánchez-Cuéllar, Silvia, Bernard, Virginie, Ancochea, Julio, Wasserman, Wyeth W., García-Rio, Francisco, Jimenez, Benilde, del Peso, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100585/
https://www.ncbi.nlm.nih.gov/pubmed/27625398
http://dx.doi.org/10.1093/nar/gkw811

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