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Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes

[Ru(phen)(2)(dppz)](2+) has been studied since the 1990s due to its ‘light-switch’ properties. It can be used as a luminescent DNA probe, with emission switched on through DNA binding. The luminescence observed is dependent on the solvent accessibility of the pyrazine nitrogen atoms, and therefore i...

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Detalles Bibliográficos
Autores principales:	Hall, James P., Keane, Páraic M., Beer, Hanna, Buchner, Katrin, Winter, Graeme, Sorensen, Thomas L., Cardin, David J., Brazier, John A., Cardin, Christine J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100598/ https://www.ncbi.nlm.nih.gov/pubmed/27599841 http://dx.doi.org/10.1093/nar/gkw753

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