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Toward Catalytic, Enantioselective Chlorolactonization of 1,2-Disubstituted Styrenyl Carboxylic Acids
[Image: see text] An investigation into the use of Lewis base catalysis for the enantioselective chlorolactonization of 1,2-disubstituted alkenoic acids is described. Two mechanistically distinct reaction pathways for catalytic chlorolactonization have been identified. Mechanistic investigation reve...
Autores principales: | Denmark, Scott E., Ryabchuk, Pavel, Burk, Matthew T., Gilbert, Bradley B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100718/ https://www.ncbi.nlm.nih.gov/pubmed/27555101 http://dx.doi.org/10.1021/acs.joc.6b01455 |
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