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The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model

Exacerbations are a hallmark of chronic obstructive pulmonary disease (COPD). Evidence suggests the presence of substantial between-individual variability (heterogeneity) in exacerbation rates. The question of whether individuals vary in their tendency towards experiencing severe (versus mild) exace...

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Detalles Bibliográficos
Autores principales: Sadatsafavi, Mohsen, Sin, Don D., Zafari, Zafar, Criner, Gerard, Connett, John E., Lazarus, Stephen, Han, Meilan, Martinez, Fernando, Albert, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100830/
https://www.ncbi.nlm.nih.gov/pubmed/27737842
http://dx.doi.org/10.1093/aje/kww085