Cargando…
Epidermal Growth Factor Receptor Cell Survival Signaling Requires Phosphatidylcholine Biosynthesis
Identification of pro-cell survival signaling pathways has implications for cancer, cardiovascular, and neurodegenerative disease. We show that the Caenorhabditis elegans epidermal growth factor receptor LET-23 (LET-23 EGFR) has a prosurvival function in counteracting excitotoxicity, and we identify...
Autores principales: | Crook, Matt, Upadhyay, Awani, Ido, Liyana J., Hanna-Rose, Wendy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100852/ https://www.ncbi.nlm.nih.gov/pubmed/27605519 http://dx.doi.org/10.1534/g3.116.034850 |
Ejemplares similares
-
Overactive EGF signaling promotes uv1 cell survival via increased phosphatidylcholine levels and suppression of SBP-1
por: Crook, Matt, et al.
Publicado: (2020) -
Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD(+) salvage pathway mutant
por: Reza, Rifath N, et al.
Publicado: (2022) -
Overactive EGF signaling suppresses a C. elegans
pnc-1 egg-laying phenotype independent of known signaling mediators.
por: Crook, Matt, et al.
Publicado: (2021) -
Cytokine secretion requires phosphatidylcholine synthesis
por: Tian, Yong, et al.
Publicado: (2008) -
Epidermal Remodeling in Caenorhabditis elegans Dauers Requires the Nidogen Domain Protein DEX-1
por: Flatt, Kristen M., et al.
Publicado: (2019)