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Epidermal Growth Factor Receptor Cell Survival Signaling Requires Phosphatidylcholine Biosynthesis

Identification of pro-cell survival signaling pathways has implications for cancer, cardiovascular, and neurodegenerative disease. We show that the Caenorhabditis elegans epidermal growth factor receptor LET-23 (LET-23 EGFR) has a prosurvival function in counteracting excitotoxicity, and we identify...

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Detalles Bibliográficos
Autores principales: Crook, Matt, Upadhyay, Awani, Ido, Liyana J., Hanna-Rose, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100852/
https://www.ncbi.nlm.nih.gov/pubmed/27605519
http://dx.doi.org/10.1534/g3.116.034850

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