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Determinants in the LIN-12/Notch Intracellular Domain That Govern Its Activity and Stability During Caenorhabditis elegans Vulval Development

Upon ligand binding, the LIN-12/Notch intracellular domain is released from its transmembrane tether to function in a nuclear complex that activates transcription of target genes. During Caenorhabditis elegans vulval development, LIN-12/Notch is activated by ligand in two of six multipotential vulva...

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Detalles Bibliográficos
Autores principales:	Deng, Yuting, Greenwald, Iva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2016
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100865/ https://www.ncbi.nlm.nih.gov/pubmed/27646703 http://dx.doi.org/10.1534/g3.116.034363

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