Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (BN) controls, which contain well-defined bloc...

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Detalles Bibliográficos
Autores principales: Kaisaki, Pamela J., Otto, Georg W., Argoud, Karène, Collins, Stephan C., Wallis, Robert H., Wilder, Steven P., Yau, Anthony C. Y., Hue, Christophe, Calderari, Sophie, Bihoreau, Marie-Thérèse, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100866/
https://www.ncbi.nlm.nih.gov/pubmed/27646706
http://dx.doi.org/10.1534/g3.116.033274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100866/
https://www.ncbi.nlm.nih.gov/pubmed/27646706
http://dx.doi.org/10.1534/g3.116.033274

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