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Genome-Wide Estimation of the Spontaneous Mutation Rate of Human Adenovirus 5 by High-Fidelity Deep Sequencing

Rates of spontaneous mutation determine the ability of viruses to evolve, infect new hosts, evade immunity and undergo drug resistance. Contrarily to RNA viruses, few mutation rate estimates have been obtained for DNA viruses, because their high replication fidelity implies that new mutations typica...

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Detalles Bibliográficos
Autores principales: Risso-Ballester, Jennifer, Cuevas, José M., Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100877/
https://www.ncbi.nlm.nih.gov/pubmed/27824949
http://dx.doi.org/10.1371/journal.ppat.1006013

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