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The Outer Pore and Selectivity Filter of TRPA1
TRPA1 (transient-receptor-potential-related ion channel with ankyrin domains) is a direct receptor or indirect effector for a wide variety of nociceptive signals, and thus is a compelling target for development of analgesic pharmaceuticals such as channel blockers. Recently, the structure of TRPA1 w...
Autores principales: | Christensen, Adam P., Akyuz, Nurunisa, Corey, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100928/ https://www.ncbi.nlm.nih.gov/pubmed/27824920 http://dx.doi.org/10.1371/journal.pone.0166167 |
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