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Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins

Apolipoprotein E4 (apoE4), the leading genetic risk factor for Alzheimer's disease (AD), is less lipidated compared to the most common and AD-benign allele, apoE3. We have recently shown that i.p. injections of the ATP-binding cassette A1 (ABCA1) agonist peptide CS-6253 to apoE mice reverse the...

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Detalles Bibliográficos
Autores principales:	Boehm-Cagan, Anat, Bar, Roni, Harats, Dror, Shaish, Aviv, Levkovitz, Hana, Bielicki, John K., Johansson, Jan O., Michaelson, Daniel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100931/ https://www.ncbi.nlm.nih.gov/pubmed/27824936 http://dx.doi.org/10.1371/journal.pone.0166195

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