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Skin Vaccination against Rotavirus Using Microneedles: Proof of Concept in Gnotobiotic Piglets
Live-attenuated oral rotavirus (RV) vaccines have lower efficacy in low income countries, and additionally are associated with a rare but severe adverse event, intussusception. We have been pursuing the development of an inactivated rotavirus vaccine (IRV) using the human rotavirus strain CDC-9 (G1P...
Autores principales: | Wang, Yuhuan, Vlasova, Anastasia, Velasquez, Daniel E., Saif, Linda J., Kandasamy, Sukumar, Kochba, Efrat, Levin, Yotam, Jiang, Baoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100943/ https://www.ncbi.nlm.nih.gov/pubmed/27824918 http://dx.doi.org/10.1371/journal.pone.0166038 |
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