Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation

The tumor microenvironment is a critical modulator of carcinogenesis; however, in many tumor types, the influence of the stroma during preneoplastic stages is unknown. Here we explored the relationship between pre-tumor cells and their surrounding stroma in malignant progression of the cerebellar tu...

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Detalles Bibliográficos
Autores principales: Bassett, Erin A, Tokarew, Nicholas, Allemano, Ema A, Mazerolle, Chantal, Morin, Katy, Mears, Alan J, McNeill, Brian, Ringuette, Randy, Campbell, Charles, Smiley, Sheila, Pokrajac, Neno T, Dubuc, Adrian M, Ramaswamy, Vijay, Northcott, Paul A, Remke, Marc, Monnier, Philippe P, Potter, David, Paes, Kim, Kirkpatrick, Laura L, Coker, Kenneth J, Rice, Dennis S, Perez-Iratxeta, Carol, Taylor, Michael D, Wallace, Valerie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100999/
https://www.ncbi.nlm.nih.gov/pubmed/27823583
http://dx.doi.org/10.7554/eLife.16764

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