Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach

Systemic sclerosis (SSc) is a multisystem disease characterized by functional and structural abnormalities of small blood vessels, fibrosis of the skin and internal organs, immune system activation, and autoimmunity. The gastrointestinal tract is involved in nearly all patients and is a source of si...

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Detalles Bibliográficos
Autores principales: Braun-Moscovici, Yolanda, Brun, Rita, Braun, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2016
Materias:
Special Issue on Rheumatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101005/
https://www.ncbi.nlm.nih.gov/pubmed/27824553
http://dx.doi.org/10.5041/RMMJ.10258
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author Braun-Moscovici, Yolanda
Brun, Rita
Braun, Marius
author_facet Braun-Moscovici, Yolanda
Brun, Rita
Braun, Marius
author_sort Braun-Moscovici, Yolanda
collection PubMed
description Systemic sclerosis (SSc) is a multisystem disease characterized by functional and structural abnormalities of small blood vessels, fibrosis of the skin and internal organs, immune system activation, and autoimmunity. The gastrointestinal tract is involved in nearly all patients and is a source of significant morbidity and even mortality. The aim of this review is to summarize the pathogenesis and to provide a clinical approach to these patients.
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spelling pubmed-51010052016-11-10 Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach Braun-Moscovici, Yolanda Brun, Rita Braun, Marius Rambam Maimonides Med J Special Issue on Rheumatology Systemic sclerosis (SSc) is a multisystem disease characterized by functional and structural abnormalities of small blood vessels, fibrosis of the skin and internal organs, immune system activation, and autoimmunity. The gastrointestinal tract is involved in nearly all patients and is a source of significant morbidity and even mortality. The aim of this review is to summarize the pathogenesis and to provide a clinical approach to these patients. Rambam Health Care Campus 2016-10-31 /pmc/articles/PMC5101005/ /pubmed/27824553 http://dx.doi.org/10.5041/RMMJ.10258 Text en © 2016 Braun-Moscovici et al. This is an open-access article. All its content, except where otherwise noted, is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Issue on Rheumatology
Braun-Moscovici, Yolanda
Brun, Rita
Braun, Marius
Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title_full Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title_fullStr Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title_full_unstemmed Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title_short Systemic Sclerosis and the Gastrointestinal Tract—Clinical Approach
title_sort systemic sclerosis and the gastrointestinal tract—clinical approach
topic Special Issue on Rheumatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101005/
https://www.ncbi.nlm.nih.gov/pubmed/27824553
http://dx.doi.org/10.5041/RMMJ.10258
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