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Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization

Viral replicase recruitment and long-range RNA interactions are essential for RNA virus replication, yet the mechanism of their interplay remains elusive. Flaviviruses include numerous important human pathogens, e.g., dengue virus (DENV) and Zika virus (ZIKV). Here, we revealed a highly conserved, c...

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Detalles Bibliográficos
Autores principales: Liu, Zhong-Yu, Li, Xiao-Feng, Jiang, Tao, Deng, Yong-Qiang, Ye, Qing, Zhao, Hui, Yu, Jiu-Yang, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101012/
https://www.ncbi.nlm.nih.gov/pubmed/27692070
http://dx.doi.org/10.7554/eLife.17636