Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

Kinetochores, multisubunit protein assemblies, connect chromosomes to spindle microtubules to promote chromosome segregation. The 10-subunit KMN assembly (comprising KNL1, MIS12, and NDC80 complexes, designated KNL1C, MIS12C, and NDC80C) binds microtubules and regulates mitotic checkpoint function t...

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Detalles Bibliográficos
Autores principales: Petrovic, Arsen, Keller, Jenny, Liu, Yahui, Overlack, Katharina, John, Juliane, Dimitrova, Yoana N., Jenni, Simon, van Gerwen, Suzan, Stege, Patricia, Wohlgemuth, Sabine, Rombaut, Pascaline, Herzog, Franz, Harrison, Stephen C., Vetter, Ingrid R., Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101189/
https://www.ncbi.nlm.nih.gov/pubmed/27881301
http://dx.doi.org/10.1016/j.cell.2016.10.005

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