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Effects of common anesthetic agents on [(18)F]flumazenil binding to the GABA(A) receptor

BACKGROUND: The availability of GABA(A) receptor binding sites in the brain can be assessed by positron emission tomography (PET) using the radioligand, [(18)F]flumazenil. However, the brain uptake and binding of this PET radioligand are influenced by anesthetic drugs, which are typically needed in...

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Detalles Bibliográficos
Autores principales: Palner, Mikael, Beinat, Corinne, Banister, Sam, Zanderigo, Francesca, Park, Jun Hyung, Shen, Bin, Hjoernevik, Trine, Jung, Jae Ho, Lee, Byung Chul, Kim, Sang Eun, Fung, Lawrence, Chin, Frederick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101239/
https://www.ncbi.nlm.nih.gov/pubmed/27826950
http://dx.doi.org/10.1186/s13550-016-0235-2