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Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia

Complement activation plays an important role in the pathogenesis of pneumonia. We hypothesized that inhibition of the complement system in the lungs by repeated treatment with nebulized plasma-derived human C1-esterase inhibitor reduces pulmonary complement activation and subsequently attenuates lu...

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Detalles Bibliográficos
Autores principales:	de Beer, Friso, Lagrand, Wim, Glas, Gerie J., Beurskens, Charlotte J. P., van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Roelofs, Joris J. T. H., Juffermans, Nicole P., Horn, Janneke, Schultz, Marcus J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2016
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101262/ https://www.ncbi.nlm.nih.gov/pubmed/27683129 http://dx.doi.org/10.1007/s12013-016-0766-1

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