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STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System

The local production of gamma interferon (IFN-γ) is important to control Toxoplasma gondii in the brain, but the basis for these protective effects is not fully understood. The studies presented here reveal that the ability of IFN-γ to inhibit parasite replication in astrocytes in vitro is dependent...

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Detalles Bibliográficos
Autores principales: Hidano, Shinya, Randall, Louise M., Dawson, Lucas, Dietrich, Hans K., Konradt, Christoph, Klover, Peter J., John, Beena, Harris, Tajie H., Fang, Qun, Turek, Bradley, Kobayashi, Takashi, Hennighausen, Lothar, Beiting, Daniel P., Koshy, Anita A., Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101356/
https://www.ncbi.nlm.nih.gov/pubmed/27834206
http://dx.doi.org/10.1128/mBio.01881-16