Cargando…

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Hepatitis C virus (HCV) species tropism is incompletely understood. We have previously shown that at the level of entry, human CD81 and occludin (OCLN) comprise the minimal set of human factors needed for viral uptake into murine cells. As an alternative approach to genetic humanization, species bar...

Descripción completa

Detalles Bibliográficos
Autores principales: von Schaewen, Markus, Dorner, Marcus, Hueging, Kathrin, Foquet, Lander, Gerges, Sherif, Hrebikova, Gabriela, Heller, Brigitte, Bitzegeio, Julia, Doerrbecker, Juliane, Horwitz, Joshua A., Gerold, Gisa, Suerbaum, Sebastian, Rice, Charles M., Meuleman, Philip, Pietschmann, Thomas, Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101358/
https://www.ncbi.nlm.nih.gov/pubmed/27834208
http://dx.doi.org/10.1128/mBio.01915-16