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Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms

The effects of Reynolds and Womersley numbers on the hemodynamics of two simplified intracranial aneurysms (IAs), that is, sidewall and bifurcation IAs, and a patient-specific IA are investigated using computational fluid dynamics. For this purpose, we carried out three numerical experiments for eac...

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Autores principales: Asgharzadeh, Hafez, Borazjani, Iman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101408/
https://www.ncbi.nlm.nih.gov/pubmed/27847544
http://dx.doi.org/10.1155/2016/7412926
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author Asgharzadeh, Hafez
Borazjani, Iman
author_facet Asgharzadeh, Hafez
Borazjani, Iman
author_sort Asgharzadeh, Hafez
collection PubMed
description The effects of Reynolds and Womersley numbers on the hemodynamics of two simplified intracranial aneurysms (IAs), that is, sidewall and bifurcation IAs, and a patient-specific IA are investigated using computational fluid dynamics. For this purpose, we carried out three numerical experiments for each IA with various Reynolds (Re = 145.45 to 378.79) and Womersley (Wo = 7.4 to 9.96) numbers. Although the dominant flow feature, which is the vortex ring formation, is similar for all test cases here, the propagation of the vortex ring is controlled by both Re and Wo in both simplified IAs (bifurcation and sidewall) and the patient-specific IA. The location of the vortex ring in all tested IAs is shown to be proportional to Re/Wo(2) which is in agreement with empirical formulations for the location of a vortex ring in a tank. In sidewall IAs, the oscillatory shear index is shown to increase with Wo and 1/Re because the vortex reached the distal wall later in the cycle (higher resident time). However, this trend was not observed in the bifurcation IA because the stresses were dominated by particle trapping structures, which were absent at low Re = 151.51 in contrast to higher Re = 378.79.
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spelling pubmed-51014082016-11-15 Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms Asgharzadeh, Hafez Borazjani, Iman Comput Math Methods Med Research Article The effects of Reynolds and Womersley numbers on the hemodynamics of two simplified intracranial aneurysms (IAs), that is, sidewall and bifurcation IAs, and a patient-specific IA are investigated using computational fluid dynamics. For this purpose, we carried out three numerical experiments for each IA with various Reynolds (Re = 145.45 to 378.79) and Womersley (Wo = 7.4 to 9.96) numbers. Although the dominant flow feature, which is the vortex ring formation, is similar for all test cases here, the propagation of the vortex ring is controlled by both Re and Wo in both simplified IAs (bifurcation and sidewall) and the patient-specific IA. The location of the vortex ring in all tested IAs is shown to be proportional to Re/Wo(2) which is in agreement with empirical formulations for the location of a vortex ring in a tank. In sidewall IAs, the oscillatory shear index is shown to increase with Wo and 1/Re because the vortex reached the distal wall later in the cycle (higher resident time). However, this trend was not observed in the bifurcation IA because the stresses were dominated by particle trapping structures, which were absent at low Re = 151.51 in contrast to higher Re = 378.79. Hindawi Publishing Corporation 2016 2016-10-26 /pmc/articles/PMC5101408/ /pubmed/27847544 http://dx.doi.org/10.1155/2016/7412926 Text en Copyright © 2016 H. Asgharzadeh and I. Borazjani. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Asgharzadeh, Hafez
Borazjani, Iman
Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title_full Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title_fullStr Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title_full_unstemmed Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title_short Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms
title_sort effects of reynolds and womersley numbers on the hemodynamics of intracranial aneurysms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101408/
https://www.ncbi.nlm.nih.gov/pubmed/27847544
http://dx.doi.org/10.1155/2016/7412926
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