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Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer

High expression of Inhibitor of apoptosis proteins (IAPs) has been related to colorectal cancer (CRC) progression, resistance to treatment and poor prognosis. TRAIL (TNF-related apoptosis-inducing ligand) through its receptors DR4 (TRAIL-R1) and DR5 (TRAIL-R2) can selectively induce cancer cell apop...

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Detalles Bibliográficos
Autores principales:	Devetzi, Marina, Kosmidou, Vivian, Vlassi, Margarita, Perysinakis, Iraklis, Aggeli, Chrysanthi, Choreftaki, Theodosia, Zografos, Georgios N., Pintzas, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101514/ https://www.ncbi.nlm.nih.gov/pubmed/27827395 http://dx.doi.org/10.1038/srep36532

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