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Potent Inducers of Endogenous Antimicrobial Peptides for Host Directed Therapy of Infections

A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vitro. In addition, oral administration of an APD in...

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Detalles Bibliográficos
Autores principales:	Ottosson, H., Nylén, F., Sarker, P., Miraglia, E., Bergman, P., Gudmundsson, G. H., Raqib, R., Agerberth, B., Strömberg, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101518/ https://www.ncbi.nlm.nih.gov/pubmed/27827460 http://dx.doi.org/10.1038/srep36692

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