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FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells

Proteins involved in genetic stability maintenance and safeguarding DNA replication act not only against cancer initiation but could also play a major role in sustaining cancer progression. Here, we report that the FANC pathway is highly expressed in metastatic melanoma harboring the oncogenic micro...

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Detalles Bibliográficos
Autores principales: Bourseguin, Julie, Bonet, Caroline, Renaud, Emilie, Pandiani, Charlotte, Boncompagni, Marina, Giuliano, Sandy, Pawlikowska, Patrycja, Karmous-Benailly, Houda, Ballotti, Robert, Rosselli, Filippo, Bertolotto, Corine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101529/
https://www.ncbi.nlm.nih.gov/pubmed/27827420
http://dx.doi.org/10.1038/srep36539