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Ischemic postconditioning and pinacidil suppress calcium overload in anoxia-reoxygenation cardiomyocytes via down-regulation of the calcium-sensing receptor

Ischemic postconditioning (IPC) and ATP sensitive potassium channel (KATP) agonists (e.g. pinacidil and diazoxide) postconditioning are effective methods to defeat myocardial ischemia-reperfusion (I/R) injury, but their specific mechanisms of reducing I/R injury are not fully understood. We observed...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Cao, Song, Deng, Shengli, Yao, Gang, Yu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101590/
https://www.ncbi.nlm.nih.gov/pubmed/27833799
http://dx.doi.org/10.7717/peerj.2612

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