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Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
BACKGROUND: Malaria, caused by Plasmodium falciparum, continues to have a devastating impact on global health, emphasizing the great need for a malaria vaccine. The circumsporozoite protein (CSP) is an attractive target for a malaria vaccine, and forms a major component of RTS,S, the most clinically...
Autores principales: | Janitzek, Christoph M., Matondo, Sungwa, Thrane, Susan, Nielsen, Morten A., Kavishe, Reginald, Mwakalinga, Steve B., Theander, Thor G., Salanti, Ali, Sander, Adam F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101663/ https://www.ncbi.nlm.nih.gov/pubmed/27825348 http://dx.doi.org/10.1186/s12936-016-1574-1 |
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