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Binding of galectin-1 to breast cancer cells MCF7 induces apoptosis and inhibition of proliferation in vitro in a 2D- and 3D- cell culture model
BACKGROUND: Galectin-1 (gal-1) belongs to the family of β-galactoside-binding proteins which primarily recognizes the Galβ1-4GlcNAc sequences of oligosaccharides associated with several cell surface glycoconjugates. The lectin recognizes correspondent glycoepitopes on human breast cancer cells. Gale...
Autores principales: | Geiger, Pamina, Mayer, Barbara, Wiest, Irmi, Schulze, Sandra, Jeschke, Udo, Weissenbacher, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101677/ https://www.ncbi.nlm.nih.gov/pubmed/27825375 http://dx.doi.org/10.1186/s12885-016-2915-8 |
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