Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the estrogen receptor 1 (ESR1) and cytochrome P450 19A1 (CYP19A1) genes have been associated with breast cancer risk, endocrine therapy response and side effects, mainly in postmenopausal women with early breast cancer. This analysis aimed to ass...

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Detalles Bibliográficos
Autores principales: Johansson, Harriet, Gray, Kathryn P., Pagani, Olivia, Regan, Meredith M., Viale, Giuseppe, Aristarco, Valentina, Macis, Debora, Puccio, Antonella, Roux, Susanne, Maibach, Rudolf, Colleoni, Marco, Rabaglio, Manuela, Price, Karen N., Coates, Alan S., Gelber, Richard D., Goldhirsch, Aron, Kammler, Roswitha, Bonanni, Bernardo, Walley, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101790/
https://www.ncbi.nlm.nih.gov/pubmed/27825388
http://dx.doi.org/10.1186/s13058-016-0771-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101790/
https://www.ncbi.nlm.nih.gov/pubmed/27825388
http://dx.doi.org/10.1186/s13058-016-0771-8

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