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PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle

BACKGROUND: Skeletal muscle tissue has an enormous regenerative capacity that is instrumental for a successful defense against muscle injury and wasting. The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) exerts therapeutic effects in several muscle pathologies, but its role in...

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Detalles Bibliográficos
Autores principales:	Dinulovic, Ivana, Furrer, Regula, Di Fulvio, Sabrina, Ferry, Arnaud, Beer, Markus, Handschin, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101792/ https://www.ncbi.nlm.nih.gov/pubmed/27833743 http://dx.doi.org/10.1186/s13395-016-0110-x

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