Cargando…
Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer
BACKGROUND: Evaluation of set up error detection by a transperineal ultrasound in comparison with a cone beam CT (CBCT) based system in external beam radiation therapy (EBRT) of prostate cancer. METHODS: Setup verification was performed with transperineal ultrasound (TPUS) and CBCT for 10 patients t...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101794/ https://www.ncbi.nlm.nih.gov/pubmed/27825386 http://dx.doi.org/10.1186/s13014-016-0722-7 |
_version_ | 1782466351503245312 |
---|---|
author | Richter, Anne Polat, Bülent Lawrenz, Ingulf Weick, Stefan Sauer, Otto Flentje, Michael Mantel, Frederick |
author_facet | Richter, Anne Polat, Bülent Lawrenz, Ingulf Weick, Stefan Sauer, Otto Flentje, Michael Mantel, Frederick |
author_sort | Richter, Anne |
collection | PubMed |
description | BACKGROUND: Evaluation of set up error detection by a transperineal ultrasound in comparison with a cone beam CT (CBCT) based system in external beam radiation therapy (EBRT) of prostate cancer. METHODS: Setup verification was performed with transperineal ultrasound (TPUS) and CBCT for 10 patients treated with EBRT for prostate cancer. In total, 150 ultrasound and CBCT scans were acquired in rapid succession and analyzed for setup errors. The deviation between setup errors of the two modalities was evaluated separately for each dimension. RESULTS: A moderate correlation in lateral, vertical and longitudinal direction was observed comparing the setup errors. Mean differences between TPUS and CBCT were (−2.7 ± 2.3) mm, (3.0 ± 2.4) mm and (3.2 ± 2.7) mm in lateral, vertical and longitudinal direction, respectively. The mean Euclidean difference between TPUS and CBCT was (6.0 ± 3.1) mm. Differences up to 19.2 mm were observed between the two imaging modalities. Discrepancies between TPUS and CBCT of at least 5 mm occurred in 58 % of monitored treatment sessions. CONCLUSION: Setup differences between TPUS and CBCT are 6 mm on average. Although the correlation of the setup errors determined by the two different image modalities is rather week, the combination of setup verification by CBCT and intrafraction motion monitoring by TPUS imaging can use the benefits of both imaging modalities. |
format | Online Article Text |
id | pubmed-5101794 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-51017942016-11-10 Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer Richter, Anne Polat, Bülent Lawrenz, Ingulf Weick, Stefan Sauer, Otto Flentje, Michael Mantel, Frederick Radiat Oncol Research BACKGROUND: Evaluation of set up error detection by a transperineal ultrasound in comparison with a cone beam CT (CBCT) based system in external beam radiation therapy (EBRT) of prostate cancer. METHODS: Setup verification was performed with transperineal ultrasound (TPUS) and CBCT for 10 patients treated with EBRT for prostate cancer. In total, 150 ultrasound and CBCT scans were acquired in rapid succession and analyzed for setup errors. The deviation between setup errors of the two modalities was evaluated separately for each dimension. RESULTS: A moderate correlation in lateral, vertical and longitudinal direction was observed comparing the setup errors. Mean differences between TPUS and CBCT were (−2.7 ± 2.3) mm, (3.0 ± 2.4) mm and (3.2 ± 2.7) mm in lateral, vertical and longitudinal direction, respectively. The mean Euclidean difference between TPUS and CBCT was (6.0 ± 3.1) mm. Differences up to 19.2 mm were observed between the two imaging modalities. Discrepancies between TPUS and CBCT of at least 5 mm occurred in 58 % of monitored treatment sessions. CONCLUSION: Setup differences between TPUS and CBCT are 6 mm on average. Although the correlation of the setup errors determined by the two different image modalities is rather week, the combination of setup verification by CBCT and intrafraction motion monitoring by TPUS imaging can use the benefits of both imaging modalities. BioMed Central 2016-11-08 /pmc/articles/PMC5101794/ /pubmed/27825386 http://dx.doi.org/10.1186/s13014-016-0722-7 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Richter, Anne Polat, Bülent Lawrenz, Ingulf Weick, Stefan Sauer, Otto Flentje, Michael Mantel, Frederick Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title | Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title_full | Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title_fullStr | Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title_full_unstemmed | Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title_short | Initial results for patient setup verification using transperineal ultrasound and cone beam CT in external beam radiation therapy of prostate cancer |
title_sort | initial results for patient setup verification using transperineal ultrasound and cone beam ct in external beam radiation therapy of prostate cancer |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101794/ https://www.ncbi.nlm.nih.gov/pubmed/27825386 http://dx.doi.org/10.1186/s13014-016-0722-7 |
work_keys_str_mv | AT richteranne initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT polatbulent initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT lawrenzingulf initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT weickstefan initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT sauerotto initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT flentjemichael initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer AT mantelfrederick initialresultsforpatientsetupverificationusingtransperinealultrasoundandconebeamctinexternalbeamradiationtherapyofprostatecancer |