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Study protocol – A systematic review and meta‐analysis of hypothermia in experimental traumatic brain injury: Why have promising animal studies not been replicated in pragmatic clinical trials?

Traumatic brain injury (TBI) is a major cause of death and permanent disability. Systemic hypothermia, a treatment used in TBI for many decades, has recently been found to be associated with neutral or unfavourable clinical outcomes despite apparently promising preclinical research. Systematic revie...

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Detalles Bibliográficos
Autores principales: Hirst, Theodore C., Watzlawick, Ralf, Rhodes, Jonathan K., Macleod, Malcolm R., Andrews, Peter J.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101852/
https://www.ncbi.nlm.nih.gov/pubmed/27867522
http://dx.doi.org/10.1002/ebm2.20